Nursing: Do You Have What It Takes?

Nursing is a challenging and demanding career, and it takes a specific kind of person to make a great nurse. There are many different types of nurse and nursing careers, and there is plenty of opportunity for career progression within the nursing industry. The journey to becoming a nurse requires many years of training and […]

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Healthy environment, healthy kidneys! The ERA-EDTA takes the lead on climate change and health

Climate change represents one of the greatest global health threats of our time. In choosing Healthy Environment, Healthy Kidneys as the theme for the 2021 fully virtual Congress, the ERA-EDTA highlights the central role of nephrologists and other health professionals in advocacy for global efforts to reduce emissions and protect against climate change.   Health […]

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Lung sonography is an useful guide to lung decongestion in hemodialysis patients at high cardiovascular risk

Dangerous lung congestion or overhydration can be detected relatively easily in dialysis patients by means of ultrasound examinations and the application of this technique is useful to safely guide lung decongestion.   In hemodialysis patients at high cardiovascular risk, including patients with coronary artery disease and heart failure, lung congestion, a condition predisposing to decompensated […]

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Dapagliflozin provides kidney protection even in cases of FSGS kidney disease

The progressive loss of renal function in focal segmental glomerulosclerosis (FSGS) was reduced by half in the DAPA-CKD study…   Many patients with the rare kidney disease FSGS require dialysis in the course of the disease, despite anti-inflammatory corticosteroid therapies. The DAPA-CKD study showed a significant benefit in renal outcomes for chronic kidney disease patients […]

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Mechanisms of kidney protection by gliflozins

There is now evidence of how SGLT2 inhibitors slow the progression of chronic kidney disease, regardless of diabetes status…   SGLT2 inhibitors (gliflozins) are oral anti-diabetic drugs. They not only reduce blood sugar, but also improve cardiovascular and renal outcomes – not only in type 2 diabetics, but also in non-diabetics. This benefit cannot be due […]

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A targeted treatment for IgA nephropathy at last?

Iptacopan, an oral, alternative complement pathway inhibitor of Factor B, could provide the first therapy targeted at one of the key drivers of IgAN…   Due to the immunological pathogenesis of IgA nephropathy (IgAN), patients used to be given immunosuppressive therapy; however, this was shown to have no long-term benefit over optimal supportive therapy. Promising […]

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The ACCOLADE study on C3 glomerulopathy

The selective C5a receptor inhibitor avacopan could be used in future to treat immune-mediated inflammatory disorders in C3G renal disease.   C3 glomerulopathy is a rare disease in which the deposition of C3 protein causes severe inflammation of the glomeruli, which can progress to end stage kidney disease requiring dialysis or transplantation. A new study […]

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